Endocrine Abstracts

Introduction: Association between high thyrotrophin receptor antibodies (TRAb) and relapse of thyroid cancer in Graves’ patients was reported previously. In this study, we aimed to investigate possible relation between TRAb and thyroid malignancies in patients with toxic multinodular (TMNG) and toxic nodular goiter (TNG).Methods: Thyroidectomized patients with a preoperative diagnosis of TMNG, TNG and euthyroid multinodular or nodular goiter (MNG/NG...

Introduction: We aimed to determine demographical, hormonal, ultrasonography(US) and cytological features of cases with neck lesions that are located outside the thyroid region and have similar echogenity with thyroid tissue.Method: Neck US reports of patients who underwent fine needle aspiration(FNAB) under US guidance in our clinic in a period of one year were reviewed retrospectively. Lesions having similar echogenity with thyroid tissue and defined a...

Introduction: Atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) termed as Bethesda Category III constitute 15–30% of thyroid cytology. However, the risk of malignancy in this heterogenous category is estimated as 5–15%. The recent studies has been reported the malignancy rate in the wide range of 6–48%. This causes surgical approach variability between different centers. We aimed to evaluate the initial malignancy rate...

Background: The characteristics of multifocal PTC remain controversial. Surgical approach to multifocal tumor changes between centers. In cases that the initial procedure was lobectomy, most clinicians would suggest for completion thyroidectomy since the risk of PTC in the contralateral lobe is significant. This study aimed to evaluate the incidence of bilateral involvement, predictive factors for bilaterality and whether or not bilaterality was related with more aggressive hi...

Introduction: Hyalinizing trabecular tumor is a very rare neoplasm of thyroid and can be misinterpreted as papillary or medullary cancer in fine needle aspiration biopsy (FNAB).Case report: Multinodular goiter was detected in a 65 years old woman using metformin and L-thyroxine for impaired blood glucose and Hashimoto thyroiditis, respectively. FNAB was performed in two nodules and reported as suspicious for malignancy and benign. She underwent total thy...

Introduction: Phaeochromocytomas (PHEO) are diagnosed with classic findings and symptoms but biochemical confirmation must be made. Either urinary or plasma chatecholamines and metanephrines can be used for biochemical evaluation. Normal values rule out the diagnosis, whereas fourfold increase above the upper limit of normal confirm the diagnosis. But value of borderline or less than fourfold elevations in the diagnosis is not clear. We aimed to determine the urinary fractiona...

Introduction: 47,XYY syndrome is characterized by an extra copy of the Y chromosome in each cells of a male. It occurs in about 1/1000 of newborn boys and most males with this syndrome have normal sexual development and fertility. They tend to have tall stature and mild motor and language developmental problems. Testosterone levels are normal. Increased rate of criminal activity in XYY males was related to a lack of judgement and lower socioeconomic status due to a lower mean ...

Objective: Polycystic ovary syndrome (PCOS) is a complex endocrinopathy affecting 5–10% of women in reproductive period. Our goal is to determine which symptoms and findings are the most common in Turkish adolescents with PCOS.Material and method: Ninety three adolescents (15–19 years old) who admitted to our outpatient clinic with at least one of the complaints (acne, obesity, menstrual irregularities and hirsutism) were enrolled in the study....

Introduction: Primary hyperparatyhyroidism (PHPT) is usually caused by single or multiple adenomas and cancer is rare accounting for <1% of all presentations. The presence of certain cytological and architectural features such as adherence to adjacent organs, a solid growth pattern, broad bands of fibrosis, cytological atypia, and an irregular growth contour do not indicate malignancy but are recognised as atypical features encountered more commonly in malignant than benig...

Introduction: Increasing evidence is available for the role of prolactin in the development of various cancers. The purpose of this study is to evaluate the frequency of thyroid cancer in patients with prolactinoma followed up at a single site.Materials and methods: Medical records of 182 patients, diagnosed with prolactinoma, were reviewed retrospectively. Out of these patients, 114 patients (103 female patients, 11 male patients, mean age 35±10.4)...